No one knows a prescription drug’s side effects like the person taking it.
Make your voice heard.
RxISK is a free, independent drug safety website to help you weigh the benefits of any medication against its potential dangers.
Could it be my meds?
All drugs have side effects, but people often don’t link the effect they are experiencing to starting, stopping, or changing the dose of a drug. RxISK provides free access to information and tools to help you assess the connection between a drug and a side effect.
Drug Search
Starting a Medication
Guides & Papers
Too Many Medications?
Post-SSRI Sexual Dysfunction
Get medication harms into your medical record
Our free Healthcare Record Pro Forma is a one page document that you can complete with details of your problem together with an official SNOMED code, and then give it to your doctor.
Explore our RxISK Zones
The RxISK Zones bring together a collection of content from our website about each type of side effect. They are aimed at giving you a good overview of the issue without having to search through lots of material.
Our zones cover suicide, violence, sex and relationships, hair, skin and nails, withdrawal, vision, and fertility.
Are you experiencing a drug side effect?
Get your free RxISK Report to find out
The RxISK Report takes 10 minutes to complete and provides you with a RxISK Score indicating how likely it is that your problem is caused by starting or stopping a prescription drug.
PSSD Research Fund
Your donations are needed to fund scientific research into post-SSRI sexual dysfunction (PSSD) and other enduring sexual dysfunctions. The aim is to better understand the biology of these conditions and hopefully find treatments.
From The Blog…
Ostriches, Doctors, SSRIs and Tylenol
In 2023 a new set of Canadian Guidelines for the Management of Alcohol Use Disorders put a serious problem on the radar for doctors that few of them likely expected. See Antidepressants, Alcohol and Anne-Marie. The antidepressants doctors commonly prescribed, often telling people these medicines would help them manage their alcohol issues, were likely causing…
Withdrawal Syndromes: Lost in Translation
Understanding Antidepressant Withdrawal © Coral Smith 2025 This post by Harriet Vogt follows on from her recent Ruptures in Clinical Care post The members of Shane Cooke and Mary Hennessey’s antidepressant withdrawal peer support group decided there was more to explore together after our first meeting. They wanted to dig deeper into their experiences of protracted…
Over-Diagnosing or Under-Diagnosing
This post follows on from Repairing Ruptures in Clinical Care and the Future of Health App-Ointments. It also links to An Appleby a Day and Tangled up in Bureaucracy. Repairing Ruptures had a lot of comments from Lucy. One of them kicks things off here. Lucy’s Struggle Since waking up to the adverse effects of…